Product Overview
QO-58 | T28483 | TargetMol Chemicals
CAS: 1259536-62-3
Smiles: Fc1cc(c(Cl)nc1Cl)-c1cc(=O)n2[nH]c(c(-c3ccccc3)c2n1)C(F)(F)F
Formula: C18H8Cl2F4N4O
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: QO-58 is a Kv7 channel opener with EC50 values of 7.0, 1.0, 5.2, 0.6 μM for Kv7.1, Kv7.2, Kv7.3/7.5, Kv7.4 respectively. QO-58 increases the pain threshold of neuropathic pain in a sciatic nerve CCI in vivo.
Molecular Weight: 443, 18
