Product Overview
Quetiapine | T0162 | TargetMol Chemicals
CAS: 111974-69-7
Smiles: OCCOCCN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12
Formula: C21H25N3O2S
Pathway: GPCR/G Protein|||Immunology/Inflammation|||Neuroscience
Target: Dopamine Receptor|||5-HT Receptor|||Adrenergic Receptor|||AChR|||Histamine Receptor
Receptor: N/A
Bioactivity: Quetiapine is used for the therapy of schizophrenia, and for the treatment of acute manic episodes associated with bipolar I disorder. The mechanism of quetiapine' action is thought by mediated through antagonist activity at serotonin and dopamine receptors. Specifically, the D1 and D2 dopamine, the α1 adrenoreceptor and α2 adrenoreceptor, and 5-HT1A and 5-HT2 serotonin receptor subtypes are antagonized. Quetiapine also can inhibit the histamine H1 receptor.
Molecular Weight: 383, 51
