Product Overview
Rebeccamycin | T16726 | TargetMol Chemicals
CAS: 93908-02-2
Smiles: CO[C@@H]1[C@@H](CO)O[C@H]([C@H](O)[C@H]1O)n1c2c(Cl)cccc2c2c3C(=O)NC(=O)c3c3c4cccc(Cl)c4[nH]c3c12
Formula: C27H21Cl2N3O7
Pathway: DNA Damage/DNA Repair
Target: Topoisomerase
Receptor: N/A
Bioactivity: Rebeccamycin is an antitumor antibiotic+ inhibits DNA topoisomerase I. Rebeccamycin appears to exert its primary antineoplastic effect by poisoning topoisomerase I. It also has a negligible effect on protein kinase C and topoisomerase II.
Molecular Weight: 570, 38