Product Overview
Regorafenib | T1792 | TargetMol Chemicals
CAS: 755037-03-7
Smiles: CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)c(F)c2)ccn1
Formula: C21H15ClF4N4O3
Pathway: Angiogenesis|||Apoptosis|||Autophagy|||MAPK|||Tyrosine Kinase/Adaptors
Target: Raf|||VEGFR|||c-RET|||PDGFR|||c-Kit|||Autophagy
Receptor: N/A
Bioactivity: Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor (IC50s: 1.5/2.5/4.2/7/13/22 nM for RET/C-RAF/VEGFR2/c-Kit/VEGFR1/PDGFRβ).
Molecular Weight: 482, 82
