Product Overview
Ribociclib hydrochloride | T15730 | TargetMol Chemicals
CAS: 1211443-80-9
Smiles: Cl.CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)N3CCNCC3)nc2n1C1CCCC1
Formula: C23H31ClN8O
Pathway: Cell Cycle/Checkpoint
Target: CDK
Receptor: N/A
Bioactivity: Ribociclib hydrochloride is a highly specific CDK4/6 inhibitor (IC50: 10 nM and 39 nM, respectively). It is over 1, 000-fold less potent against the cyclin B/CDK1 complex.
Molecular Weight: 471, 01