Product Overview
Ribociclib succinate hydrate | T15731 | TargetMol Chemicals
CAS: 1374639-79-8
Smiles: O=C(N(C)C)C(N1C2CCCC2)=CC(C1=N3)=CN=C3NC(N=C4)=CC=C4N5CCNCC5.OC(CCC(O)=O)=O.[F, Cl, Br, I].O
Formula: C27H38N8O6
Pathway: Cell Cycle/Checkpoint
Target: CDK
Receptor: N/A
Bioactivity: Ribociclib succinate hydrate is a highly specific CDK4/6 inhibitor (IC50s: 10 nM and 39 nM, respectively). It also is over 1, 000-fold less potent against the cyclin B/CDK1 complex.
Molecular Weight: 570, 64
