Product Overview
RO-0335 | T9223 | TargetMol Chemicals
CAS: 867365-76-2
Smiles: NS(c(cc1)cc(Cl)c1NC(Cc(ccc(Br)c1Oc2cc(Cl)cc(C#N)c2)c1F)=O)(=O)=O
Formula: C21H13BrCl2FN3O4S
Pathway: Microbiology/Virology
Target: Reverse Transcriptase
Receptor: N/A
Bioactivity: RO-0335 is a potent diphenylether nonnucleoside reverse transcriptase inhibitor. RO-0335 inhibits Wt HIV-1 (IC50 = 1.1 nM) and retained activity (IC50< 100 nM) against 92% of a large number of NNRTI-resistant clinical isolates.
Molecular Weight: 573, 22
