Product Overview
Ro 08-2750 | T16766 | TargetMol Chemicals
CAS: 37854-59-4
Smiles: Cc1cc2nc3c(nc(=O)[nH]c3=O)n(C)c2cc1C=O
Formula: C13H10N4O3
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: Ro 08-2750 is a non-peptide and reversible nerve growth factor (NGF) inhibitor which binds to NGF, and with an IC50 of ~ 1 µM. Ro 08-2750 is a selective MSI RNA-binding activity inhibitor, with an IC50 of 2.7 μM. Ro 08-2750 inhibits NGF binding to p75NTR selectively over TRKA.
Molecular Weight: 270, 248