Product Overview
Ro 5126766 | T6971 | TargetMol Chemicals
CAS: 946128-88-7
Smiles: CNS(=O)(=O)Nc1nccc(Cc2c(C)c3ccc(Oc4ncccn4)cc3oc2=O)c1F
Formula: C21H18FN5O5S
Pathway: MAPK
Target: Raf|||MEK
Receptor: N/A
Bioactivity: RO5126766 (CH5126766) is a dual RAF/MEK inhibitor with IC50 of 8.2 nM, 19 nM, 56 nM, and 160 nM for BRAF V600E, BRAF, CRAF, and MEK1, respectively. Phase 1.
Molecular Weight: 471, 46
