RO-5963 | T16771

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TMC-T16771
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Product Overview

RO-5963 | T16771 | TargetMol Chemicals

CAS: 1416663-77-8

Smiles: Cc1c(Cl)ccc2c(\C=C3\NC(=O)N(C(C(=O)NC(CO)CO)c4ccc(F)c(F)c4)C3=O)c[nH]c12

Formula: C24H21ClF2N4O5

Pathway: Apoptosis

Target: Mdm2

Receptor: N/A

Bioactivity: RO-5963 is a dual inhibitor of p53-MDM2 and p53-MDMX (IC50s: ~17 nM and ~24 nM, respectively).

Molecular Weight: 518, 9

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