Product Overview
Ro 90-7501 | T16773 | TargetMol Chemicals
CAS: 293762-45-5
Smiles: Nc1ccc(cc1)-c1nc2ccc(cc2[nH]1)-c1nc2ccc(N)cc2[nH]1
Formula: C20H16N6
Pathway: DNA Damage/DNA Repair|||PI3K/Akt/mTOR signaling
Target: ATM/ATR
Receptor: N/A
Bioactivity: Ro 90-7501 is an amyloid β42 fibril assembly inhibitor (EC50: 2 μM). Ro 90-7501 inhibits ATM phosphorylation and DNA repair. Ro 90-7501 also inhibits PP5 in a TPR-dependent manner. RO 90-7501 selectively enhances TLR3 and RLR ligand-induced IFN-β gene expression and antiviral response.
Molecular Weight: 340, 39
