Product Overview
Ruxolitinib phosphate | T3043 | TargetMol Chemicals
CAS: 1092939-17-7
Smiles: OP(O)(O)=O.N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Formula: C17H21N6O4P
Pathway: Angiogenesis|||Autophagy|||Chromatin/Epigenetic|||JAK/STAT signaling|||Stem Cells
Target: Mitophagy|||JAK|||Autophagy
Receptor: N/A
Bioactivity: Ruxolitinib phosphate(INCB018424 phosphate) is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM, >130-fold selectivity for JAK1/2 versus JAK3.
Molecular Weight: 404, 367
