Product Overview
Ruxolitinib | T1829 | TargetMol Chemicals
CAS: 941678-49-5
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Formula: C17H18N6
Pathway: Angiogenesis|||Apoptosis|||Autophagy|||Chromatin/Epigenetic|||JAK/STAT signaling|||Stem Cells|||Tyrosine Kinase/Adaptors
Target: Apoptosis|||Mitophagy|||Tyrosine Kinases|||JAK|||Autophagy
Receptor: N/A
Bioactivity: Ruxolitinib is a potent and selective JAK1/2 inhibitor (IC50: 3.3/2.8 nM) and is relatively less selective for JAK3 (IC50: 322 nM).
Molecular Weight: 306, 37
