Product Overview
Sacubitril | T4574 | TargetMol Chemicals
CAS: 149709-62-6
Smiles: CCOC(=O)[C@H](C)C[C@@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)CCC(O)=O
Formula: C24H29NO5
Pathway: Metabolism
Target: Neprilysin
Receptor: N/A
Bioactivity: AHU-377 is a potent NEP inhibitor with an IC50 of 5 nM. AHU-377 is a component of the heart failure medicine LCZ696.
Molecular Weight: 411, 49
