Product Overview
Sanggenol L | TN2177 | TargetMol Chemicals
CAS: 329319-20-2
Smiles: CC(C)=CCCC1(C)Oc2cc(O)c3C(=O)CC(Oc3c2C=C1)c1ccc(O)cc1O
Formula: C25H26O6
Pathway: Cell Cycle/Checkpoint|||NF-Κb
Target: c-Myc|||NF-κB
Receptor: N/A
Bioactivity: Sanggenol L shows higher cytotoxicity against human oral tumor cell lines (HSC-2 and HSG) than against normal human gingival fibroblasts (HGF), it induces apoptosis via caspase activation and inhibition of NF-κB/IκBα± phosphorylation as a potent chemotherapeutic agent for ovarian cancers.
Molecular Weight: 422, 477
