Product Overview
SB-747651A | T28695 | TargetMol Chemicals
CAS: 607372-46-3
Smiles: CCn1c(nc2cncc(CNC3CCNCC3)c12)-c1nonc1N
Formula: C16H22N8O
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: SB-747651A is a potent, ATP-competitive inhibitor of mitogen- and stress-activated kinase 1 (MSK1, IC50 = 11 nM). It targets the N-terminal kinase domain. SB-747651A inhibits MSK1, MSK2, PKA, PKB, RSK and p70S6K activity in cells.
Molecular Weight: 342, 407
