Sematilide hydrochloride | T3574

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TMC-T3574
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Product Overview

Sematilide hydrochloride | T3574 | TargetMol Chemicals

CAS: 101526-62-9

Smiles: Cl.CCN(CC)CCNC(=O)c1ccc(NS(C)(=O)=O)cc1

Formula: C14H24ClN3O3S

Pathway: Membrane transporter/Ion channel

Target: Potassium Channel

Receptor: N/A

Bioactivity: Sematilide (CK-1752) is a class III antiarrhythmic. It is a selectively delayed rectifier K+ current (IKr) channel blocker. It inhibits rapidly activating Ik in guinea pig atrial myocytes, resulting in the prolongation of refractoriness and action potential duration.

Molecular Weight: 349, 87

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