Product Overview
Sitagliptin | T0242 | TargetMol Chemicals
CAS: 486460-32-6
Smiles: N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cc(F)c(F)cc1F
Formula: C16H15F6N5O
Pathway: Autophagy|||Proteases/Proteasome|||Ubiquitination
Target: Proteasome|||DPP-4|||Autophagy
Receptor: N/A
Bioactivity: Sitagliptin, a new oral hypoglycemic (anti-diabetic drug), is a new dipeptidyl peptidase-4 (DPP-4) inhibitor. This enzyme-inhibiting drug is used either alone or in combination with metformin or thiazolidinedione for treatment of type 2 diabetes mellitus. The drug can competitively inhibit a protein/enzyme and DPP-4, that leads to an incremental amount of active incretins (GLP-1 and GIP), the diminished amount of release of glucagon and increased release of insulin.
Molecular Weight: 407, 32
