Product Overview
SKI V | T8461 | TargetMol Chemicals
CAS: 24418-86-8
Smiles: Oc1ccc(\C=C2\Oc3ccccc3C2=O)cc1O
Formula: C15H10O4
Pathway: Apoptosis|||GPCR/G Protein|||PI3K/Akt/mTOR signaling
Target: Apoptosis|||PI3K|||S1P Receptor
Receptor: N/A
Bioactivity: SKI V is a potent and noncompetitive non-lipid sphingosine kinase (SPHK; SK) inhibitor (GST-hSK, IC50 : 2 μM), and is a PI3K inhibitor(hPI3k, IC50 : 6 μM), induces apoptosis and has antitumor activity
Molecular Weight: 254, 241
