Product Overview
Sophoflavescenol | TN2217 | TargetMol Chemicals
CAS: 216450-65-6
Smiles: COc1cc(O)c(CC=C(C)C)c2oc(c(O)c(=O)c12)-c1ccc(O)cc1
Formula: C21H20O6
Pathway: Metabolism|||Neuroscience|||Others
Target: Others|||Beta-Secretase|||BACE|||PDE|||AChR|||AChE
Receptor: N/A
Bioactivity: Sophoflavescenol is a mixed inhibitor of PDE5 with a K(i) value of 0.005 microM. Sophoflavescenol has antioxidant, anti-inflammatory, and apoptotic effects, these effects might contribute to the antitumor activity without severe side effects. Sophoflavescenol exerts notable anti-inflammatory activity by inhibiting nitric oxide generation and tert-butylhydroperoxide-induced ROS generation rather than inhibiting nuclear factor kappa B activation in RAW 264.7 cells.
Molecular Weight: 368, 385