Product Overview
Sorafenib | T0093L | TargetMol Chemicals
CAS: 284461-73-0
Smiles: CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)ccn1
Formula: C21H16ClF3N4O3
Pathway: Angiogenesis|||Apoptosis|||Autophagy|||Cell Cycle/Checkpoint|||MAPK|||Tyrosine Kinase/Adaptors
Target: Apoptosis|||Raf|||VEGFR|||FLT|||Ferroptosis|||PDGFR|||c-Kit|||Autophagy
Receptor: N/A
Bioactivity: Sorafenib is a potent multikinase inhibitor (IC50s: 6/20/22 nM for Raf-1/VEGFR-4/B-Raf).
Molecular Weight: 464, 83