Product Overview
Sorafenib tosylate | T0093 | TargetMol Chemicals
CAS: 475207-59-1
Smiles: Cc1ccc(cc1)S(O)(=O)=O.CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)ccn1
Formula: C28H24ClF3N4O6S
Pathway: Angiogenesis|||Apoptosis|||Autophagy|||Cell Cycle/Checkpoint|||MAPK|||Tyrosine Kinase/Adaptors
Target: Apoptosis|||Raf|||VEGFR|||FLT|||Ferroptosis|||PDGFR|||c-Kit|||Autophagy
Receptor: N/A
Bioactivity: Sorafenib is a potent multikinase inhibitor (IC50s: 6/20/22 nM for Raf-1/VEGFR-3/B-Raf).
Molecular Weight: 637, 03
