Product Overview
SP600125 | T3109 | TargetMol Chemicals
CAS: 129-56-6
Smiles: O=C1c2ccccc2-c2[nH]nc3cccc1c23
Formula: C14H8N2O
Pathway: Apoptosis|||Autophagy|||Cell Cycle/Checkpoint|||Chromatin/Epigenetic|||MAPK|||Tyrosine Kinase/Adaptors
Target: Apoptosis|||Ferroptosis|||Trk receptor|||JNK|||Aurora Kinase|||Autophagy
Receptor: N/A
Bioactivity: SP600125 is a JNK1/2/3 inhibitor (IC50: 40/40/90 nM) and 10-fold higher selectivity than MKK4, 25-fold higher selectivity than MKK3, MKK6, PKCα, and PKB.
Molecular Weight: 220, 231