Product Overview
SPI-112 | T4340 | TargetMol Chemicals
CAS: 1051387-90-6
Smiles: OC(=O)c1cccc(N\N=C2/C(=O)Nc3ccc(cc23)S(=O)(=O)NCc2ccc(F)cc2)c1
Formula: C22H17FN4O5S
Pathway: Metabolism
Target: Phosphatase
Receptor: N/A
Bioactivity: SPI-112, the SPI-112 methyl ester analog, can inhibit cellular Shp2 PTP activity. SPI-112 bound to Shp2 by surface plasmon resonance (SPR) and displayed competitive inhibitor kinetics to Shp2.
Molecular Weight: 468, 46
