Product Overview
SU4312 | T3570 | TargetMol Chemicals
CAS: 5812-07-7
Smiles: CN(C)c1ccc(C=C2C(=O)Nc3ccccc23)cc1
Formula: C17H16N2O
Pathway: Angiogenesis|||Tyrosine Kinase/Adaptors
Target: VEGFR|||PDGFR
Receptor: N/A
Bioactivity: SU-4312, also known as DMBI, is a potent and selective inhibitor of VEGFR and PDGFR tyrosine kinases (IC50 values are 0.8 and 19.4 μM respectively). SU4312 unexpectedly protects against MPP(+) -induced neurotoxicity via selective and direct inhibition of neuronal NOS.
Molecular Weight: 264, 328
