Product Overview
Sunitinib Malate | T0374 | TargetMol Chemicals
CAS: 341031-54-7
Smiles: O[C@@H](CC(O)=O)C(O)=O.CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C
Formula: C26H33FN4O7
Pathway: Angiogenesis|||Apoptosis|||Autophagy|||Cell Cycle/Checkpoint|||Tyrosine Kinase/Adaptors
Target: Apoptosis|||Mitophagy|||VEGFR|||FLT|||IRE1|||PDGFR|||c-Kit|||Autophagy
Receptor: N/A
Bioactivity: Sunitinib is an indolinone-based tyrosine kinase inhibitor. It blocks the tyrosine kinase activities of VEGFR2, PDGFRβ (IC50: 80/2 nM), and c-kit.
Molecular Weight: 532, 569
