Product Overview
Sunitinib | T0374L | TargetMol Chemicals
CAS: 557795-19-4
Smiles: CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C
Formula: C22H27FN4O2
Pathway: Angiogenesis|||Apoptosis|||Autophagy|||Cell Cycle/Checkpoint|||Tyrosine Kinase/Adaptors
Target: Apoptosis|||Mitophagy|||VEGFR|||FLT|||IRE1|||PDGFR|||c-Kit|||Autophagy
Receptor: N/A
Bioactivity: Sunitinib, a multi-targeted RTK inhibitor, is targeting PDGFRβ and VEGFR2 (Flk-1) with IC50 of 2 nM and 80 nM and also inhibits c-Kit.
Molecular Weight: 398, 482
