Product Overview
Tadalafil | T1398 | TargetMol Chemicals
CAS: 171596-29-5
Smiles: C1N(C(=O)[C@@H]2N(C1=O)[C@@H](c1c(C2)c2c([nH]1)cccc2)c1ccc2c(c1)OCO2)C
Formula: C22H19N3O4
Pathway: Apoptosis|||Metabolism
Target: Apoptosis|||PDE
Receptor: N/A
Bioactivity: Tadalafil is a carboline-based compound with vasodilatory activity. Tadalafil selectively inhibits the cyclic guanosine monophosphate (cGMP)-specific type 5 phosphodiesterase- (PDE-5)-mediated degradation of cGMP, which is found in the smooth muscle of the corpus cavernosa and corpus spongiosum of the penis. Inhibition of cGMP degradation by tadalafil results in prolonged muscle relaxation, vasodilation, and blood engorgement of the corpus cavernosa, and, so, prolonged penile erection.
Molecular Weight: 389, 4
