Product Overview
Temsirolimus | T2145 | TargetMol Chemicals
CAS: 162635-04-3
Smiles: CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C/C=C/C=C(C)/[C@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1OC(=O)C(C)(CO)CO
Formula: C56H87NO16
Pathway: Apoptosis|||Autophagy|||PI3K/Akt/mTOR signaling
Target: Apoptosis|||mTOR|||Autophagy
Receptor: N/A
Bioactivity: Temsirolimus is a specific mTOR inhibitor ( IC50: 1.76 μM), used in the treatment of advanced renal cell cancer.
Molecular Weight: 1030, 303