Product Overview
Tesevatinib | TQ0166 | TargetMol Chemicals
CAS: 781613-23-8
Smiles: COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OC[C@H]1C[C@H]2CN(C)C[C@H]2C1
Formula: C24H25Cl2FN4O2
Pathway: Angiogenesis|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors
Target: EGFR|||VEGFR|||FLT|||Ephrin Receptor
Receptor: N/A
Bioactivity: Tesevatinib is an orally available, multi-target tyrosine kinase inhibitor (IC50s: 0.3, 16, 1.5, 8.7, and 1.4 nM for EGFR, ErbB2, KDR, Flt4, and EphB4).
Molecular Weight: 491, 39