Tilifodiolide | TN5147

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TMC-TN5147
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Product Overview

Tilifodiolide | TN5147 | TargetMol Chemicals

CAS: 126724-95-6

Smiles: O=C1OCC=C1[C@H]1CCc2ccc3C(=O)O[C@@H](c4ccoc4)c3c2C1

Formula: C20H16O5

Pathway: Apoptosis|||Immunology/Inflammation|||Membrane transporter/Ion channel|||Neuroscience

Target: IL Receptor|||TNF|||GABA Receptor

Receptor: N/A

Bioactivity: Tilifodiolide exerts in vitro and in vivo anti-inflammatory activity and in vivo antinociceptive effects. Tilifodiolide exerted antidiarrheal activity by decreasing the intestinal fluid accumulation and vasorelaxant effects mediated by nitric oxide and cyclic guanosine monophosphate, it also showed anxiolytic and antidepressant effects by the partial involvement of gamma-Aminobutyric acid (GABA) receptors and the possible participation of α2-adrenoreceptors, respectively.

Molecular Weight: 336, 3

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