Product Overview
TL-895 | T9705 | TargetMol Chemicals
CAS: 1415823-49-2
Smiles: C=CC(N(CC1)CCC1(CNc1ncnc(N)c1-c(cc1)ccc1Oc1ccccc1)F)=O
Formula: C25H26FN5O2
Pathway: Angiogenesis|||Tyrosine Kinase/Adaptors
Target: BTK
Receptor: N/A
Bioactivity: TL-895 is an ATP-competitive, and highly selective irreversible inhibitor of Bruton’s Tyrosine Kinase(BTK). TL-895 showed good potency with an IC50 of 1.5 nM and a Ki of 11.9 nM.
Molecular Weight: 447, 5