tumor protein p53 binding protein fragment [Homo sapiens]/[Mus musculus] | TP2299

tumor protein p53 binding protein fragment [Homo sapiens]/[Mus musculus] | TP2299 | TargetMol Chemicals

CAS: TP2299

Smiles: OC(C=C1)=CC=C1CC(N)C(NC(CC(C)C)C(NC(CC2=CN=CN2)C(NC(C(C)C)C(NC(CCC(O)=O)C(N3CCCC3C(NC(CCC(O)=O)C(NC(CCCCN)C(NC(CCC(O)=O)C(NC(C(C)C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

Formula: C57H87N13O18

Pathway: Others

Target: Others

Receptor: N/A

Bioactivity: Tumor protein p53 binding protein (53BP1) has been identified in a yeast two-hybrid screen as a protein that interacts with the central DNA–binding domain of p532. Similar to breast cancer susceptibility gene 13, 4 (BRCA1; 53BP1 enhances p53-dependent transcription5. Interestingly, the COOH terminus of 53BP1 contains tandem BRCA1 COOH terminus (BRCT) motifs.

Molecular Weight: 1242, 38