Product Overview
UK-122 TFA salt | T29051 | TargetMol Chemicals
CAS: 1186653-73-5
Smiles: OC(=O)C(F)(F)F.NC(=N)c1ccc(\C=C2\N=C(OC2=O)c2ccccc2)cc1
Formula: C19H14F3N3O4
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: UK-122 is a potent and selective uPA inhibitor (Ki = 20 nM). The IC(50) of UK122 in a cell-free indirect uPA assay is 0.2 micromol/L. UK122 showed little cytotoxicity against CFPAC-1 cells (IC(50) > 100 micromol/L) but significantly inhibited the migration and invasion of this pancreatic cancer cell line.
Molecular Weight: 405, 333
