Product Overview
UNC926 | T4012 | TargetMol Chemicals
CAS: 1184136-10-4
Smiles: Brc1cccc(c1)C(=O)N1CCC(CC1)N1CCCC1
Formula: C16H21BrN2O
Pathway: Chromatin/Epigenetic
Target: Epigenetic Reader Domain
Receptor: N/A
Bioactivity: UNC-926 inhibits L3MBTL1 (IC50: 3.9 μM). UNC-926 also exhibits a low micromolar affinity for L3MBTL3. UNC-926 inhibits binding of the 3xMBT domain to H4K20me1. It selectively and dose-dependently inhibits the L3MBTL13xMBT-H4K20me1 interaction. UNC-926 has not an effect on the binding of 53BP1 to H4K20me1.
Molecular Weight: 337, 261
