Product Overview
Urolithin B | T13265 | TargetMol Chemicals
CAS: 1139-83-9
Smiles: Oc1ccc2c(c1)oc(=O)c1ccccc21
Formula: C13H8O3
Pathway: Cytoskeletal Signaling|||MAPK|||Metabolism|||NF-Κb|||PI3K/Akt/mTOR signaling
Target: ERK|||NF-κB|||Akt|||Endogenous Metabolite|||JNK|||AMPK
Receptor: N/A
Bioactivity: Urolithin B inhibits NF-κB activity by reducing the phosphorylation and degradation of IκBα, and suppresses the phosphorylation of JNK, ERK, and Akt, and enhances the phosphorylation of AMPK. Urolithin B is also a regulator of skeletal muscle mass.Urolithin B is one of the gut microbial metabolites of ellagitannins, and has anti-inflammatory and antioxidant effects.
Molecular Weight: 212, 204
