Product Overview
Vesnarinone | T3465 | TargetMol Chemicals
CAS: 81840-15-5
Smiles: COc1ccc(cc1OC)C(=O)N1CCN(CC1)c1ccc2NC(=O)CCc2c1
Formula: C22H25N3O4
Pathway: Metabolism|||Microbiology/Virology|||Proteases/Proteasome
Target: HIV Protease|||PDE
Receptor: N/A
Bioactivity: Vesnarinone (INN) is a mixed phosphodiesterase 3 inhibitor and ion-channel modifier that has modest, dose-dependent, positive inotropic activity, but minimal negative chronotropic activity. It also suppresses cell proliferation and induces apoptosis by inducing the expression of p21, an inhibitor of cyclin-dependent kinase activity in p53-mediated cell cycle arrest.
Molecular Weight: 395, 459