Product Overview
VH-298 | TQ0121 | TargetMol Chemicals
CAS: 2097381-85-4
Smiles: CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)C2(CC2)C#N)C(C)(C)C)C=C1
Formula: C27H30N5O4S
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: VH-298 is a potent inhibitor of VHL that stabilizes HIF-α and elicits a hypoxic response via a different mechanism, that is the blockade of the VHL:HIF-α protein-protein interaction downstream of HIF-α hydroxylation by PHD enzymes.
Molecular Weight: 523, 65
