Product Overview
Vitexilactone | TN5243 | TargetMol Chemicals
CAS: 61263-49-8
Smiles: C[C@@H]1C[C@@H](OC(C)=O)C2C(C)(C)CCC[C@]2(C)[C@@]1(O)CCC1=CC(=O)OC1
Formula: C22H34O5
Pathway: Immunology/Inflammation|||Microbiology/Virology|||Proteases/Proteasome
Target: NADPH-oxidase|||HIV Protease|||Antifection
Receptor: N/A
Bioactivity: Vitexilactone is a HIV-1 reverse transcriptase inhibitor in virtual screening against Indonesian Herbal Database using AutoDock4 performed on HIV-1 reverse transcriptase. It has trypanocidal activity, the minimum lethal concentration against epimastigotes of Trypanosoma cruzi is 66 microM.Vitexilactone is one anticancer component of Vitex trifolia L., which exerts its anti-proliferative effect on cancer cells through inducing apoptosis and inhibiting the cell cycle.
Molecular Weight: 378, 5