Product Overview
Voleneol | TN5248 | TargetMol Chemicals
CAS: 70389-88-7
Smiles: CC(C)[C@@H]1CC[C@@]2(C)[C@H](O)CCC(=C)[C@@H]2[C@H]1O
Formula: C15H26O2
Pathway: GPCR/G Protein|||Immunology/Inflammation|||Neuroscience
Target: NOS|||COX|||Prostaglandin Receptor
Receptor: N/A
Bioactivity: 1β, 6α-Dihydroxyeudesm-4(15)-ene (Voleneol, DE) can attenuate the lipopolysaccharide (LPS)-induced inflammation in BV2 microglial cells, it also can dose-dependently suppress the protein expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2), suggest thats DE may be a good candidate to regulate LPS-induced inflammatory response.
Molecular Weight: 238, 4