Product Overview
Voxtalisib | T7014 | TargetMol Chemicals
CAS: 934493-76-2
Smiles: CCn1c2nc(N)nc(C)c2cc(-c2cc[nH]n2)c1=O
Formula: C13H14N6O
Pathway: DNA Damage/DNA Repair|||PI3K/Akt/mTOR signaling
Target: DNA-PK|||PI3K|||mTOR
Receptor: N/A
Bioactivity: Voxtalisib (SAR245409, XL765) is a dual inhibitor of mTOR/PI3K, mostly for p110γ with IC50 of 9 nM; also inhibits DNA-PK and mTOR. Phase 1/2.
Molecular Weight: 270, 296