Product Overview
VR23 | T7016 | TargetMol Chemicals
CAS: 1624602-30-7
Smiles: [O-][N+](=O)c1ccc(c(c1)[N+]([O-])=O)S(=O)(=O)N1CCN(CC1)c1ccnc2cc(Cl)ccc12
Formula: C19H16ClN5O6S
Pathway: Apoptosis|||Proteases/Proteasome|||Ubiquitination
Target: Apoptosis|||Proteasome|||Caspase
Receptor: N/A
Bioactivity: VR23 is a potent proteasome inhibitor. Data shows IC50 =1 nM for trypsin-like proteasomes, IC50=50-100 nM for chymotrypsin-like proteasomes, and IC50=3 μM for caspase-like proteasomes.
Molecular Weight: 477, 88