Product Overview
WAY-213613 | T13330L | TargetMol Chemicals
CAS: 868359-05-1
Smiles: N[C@@H](CC(=O)Nc1ccc(Oc2cc(F)c(F)cc2Br)cc1)C(O)=O
Formula: C16H13BrF2N2O4
Pathway: Metabolism
Target: transporter
Receptor: N/A
Bioactivity: WAY-213613 is a potent and selective nonsubstrate reuptake inhibitor of GLT-1/EAAT2 (IC50: 85 nM EAAT2). It displays 59- and 44-fold selectivity over EAAT1 and EAAT3 (IC50s: 5 and 3.8 μM, respectively). WAY-213613 shows no activity at ionotropic and metabotropic glutamate receptors.
Molecular Weight: 415, 191
