Product Overview
WAY-600 | T6730 | TargetMol Chemicals
CAS: 1062159-35-6
Smiles: C(N1CCC(CC1)N1N=CC2=C1N=C(N=C2N1CCOCC1)C1=CC2=C(NC=C2)C=C1)C1=CC=CN=C1
Formula: C28H30N8O
Pathway: Angiogenesis|||PI3K/Akt/mTOR signaling|||Tyrosine Kinase/Adaptors
Target: VEGFR|||PI3K|||Src|||mTOR
Receptor: N/A
Bioactivity: WAY-600 is a potent, ATP-competitive and selective inhibitor of mTOR with IC50 of 9 nM; blocks mTORC1/P-S6K(T389) and mTORC2/P-AKT(S473) but not P-AKT(T308); selective for mTOR than PI3Kα (>100-fold) and PI3Kγ (>500-fold).
Molecular Weight: 494, 59
