Product Overview
Wilfortrine | TN2308 | TargetMol Chemicals
CAS: 37239-48-8
Smiles: CC(=O)OC[C@]12[C@H](OC(C)=O)[C@H](OC(C)=O)[C@@H]3[C@@H](OC(C)=O)[C@]11O[C@@]3(C)COC(=O)c3cccnc3CC[C@@](C)(O)C(=O)O[C@@H]([C@H](OC(=O)c3ccoc3)[C@@H]2OC(C)=O)[C@]1(C)O
Formula: C41H47NO20
Pathway: Apoptosis
Target: BCL
Receptor: N/A
Bioactivity: Wilfortrine can induce liver cancer cell HepG2 apoptosis, but with no effect on the cell cycle, mainly by promoting Bax expression and inhibiting anti-apoptotic protein Bcl-2 expression.
Molecular Weight: 873, 814