Product Overview
WYE-132 | T6346 | TargetMol Chemicals
CAS: 1144068-46-1
Smiles: CNC(=O)Nc1ccc(cc1)-c1nc(N2CC3CCC(C2)O3)c2cnn(C3CCC4(CC3)OCCO4)c2n1
Formula: C27H33N7O4
Pathway: Apoptosis|||PI3K/Akt/mTOR signaling
Target: Apoptosis|||mTOR
Receptor: N/A
Bioactivity: WYE-125132 (WYE-132) is a highly potent, ATP-competitive mTOR inhibitor with IC50 of 0.19 nM; highly selective for mTOR versus PI3Ks or PI3K-related kinases hSMG1 and ATR.
Molecular Weight: 519, 606