Product Overview
XL177A | T9122 | TargetMol Chemicals
CAS: 2417089-74-6
Smiles: O=C(NC1=CC(N=CN2CC3(O)CCN(C([C@H](CC4=CC=CC=C4)CCCNC(C5=CC(N=C(CCCC6)C6=C7Cl)=C7C=C5)=O)=O)CC3)=C(C=C1)C2=O)CCN8CCN(C)CC8
Formula: C48H57ClN8O5
Pathway: Cell Cycle/Checkpoint|||DNA Damage/DNA Repair|||Ubiquitination
Target: DUB
Receptor: N/A
Bioactivity: XL177A is a selective irreversible USP7 inhibitor(IC50 : 0.34 nM). XL177A elicits cancer cell killing through a p53-dependent mechanism.
Molecular Weight: 861, 47