Product Overview
Yangambin | TN2322 | TargetMol Chemicals
CAS: 13060-14-5
Smiles: COc1cc(cc(OC)c1OC)[C@H]1OC[C@H]2[C@@H]1CO[C@@H]2c1cc(OC)c(OC)c(OC)c1
Formula: C24H30O8
Pathway: GPCR/G Protein|||Membrane transporter/Ion channel|||Metabolism
Target: Calcium Channel|||PAFR
Receptor: N/A
Bioactivity: Yangambin is a selective antagonist of the cardiovascular effects of platelet activating factor (PAF); it has hypotensive effect, which is probably due to a peripheral vasodilatation that involves, at least, the inhibition the Ca2+ influx through voltage-gated Ca2+ channels. Yangambin has central nervous system activity, it presents a depressant activity in the open field, forced swimming and pentobarbital sleeping time tests.
Molecular Weight: 446, 496
