Product Overview
Zimlovisertib | TQ0167 | TargetMol Chemicals
CAS: 1817626-54-2
Smiles: CC[C@H]1[C@@H](COc2nccc3cc(C(N)=O)c(OC)cc23)NC(=O)[C@H]1F
Formula: C18H20FN3O4
Pathway: Immunology/Inflammation|||NF-Κb
Target: IRAK
Receptor: N/A
Bioactivity: PF06650833 is an effective, selective and orally active inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK4) (IC50s: 0.2 and 2.4 nM in the cell and PBMC assay).
Molecular Weight: 361, 373