Product Overview
ZIP | TP1924 | TargetMol Chemicals
CAS: 863987-12-6
Smiles:
Formula: C90H154N30O17
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: Novel, cell-permeable inhibitor of protein kinase Mζ (PKMζ), a constitutively active, atypical PKC isozyme involved in LTP maintenance. Selectively blocks PKMζ-induced synaptic potentiation in hippocampal slices in vitro. Reverses late-phase LTP (IC50 = 1 - 2.5 μM) and produces persistent loss of 1-day-old spatial memory following central administration in vivo.
Molecular Weight: 1928, 4
